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Strawberries – Migraine Trigger

Strawberries – Migraine Trigger


Today's focus is on strawberries as a possible migraine trigger

We took a look at watermelon and tyramine in this article some time ago. We also discussed bananas and the tyramine content in this particular fruit. As mentioned then, tyramine is a biogenic amine and builds quickly during the aging process. It could be triggering your migraines. Therefore, it becomes important to apply proper handling and storage in order to minimize food spoilage, as much as possible.

As a general rule, you never want to eat foods that have been sitting for more than two days, and arguably, one day may be the maximum in most cases. Even when you are refrigerating fruits and vegetables, you may find it difficult to consume anything but the freshest of candidates. But what constitutes fresh? For watermelon, the over-ripeness could clearly be seen by cutting through the fruit. If you suffer from migraines, chances are good that you should avoid watermelon altogether. However, if you feel like taking a risk, areas that are too red, yellow, or “mushy” should be avoided.

Without further ado, let’s now turn to the delicious strawberry, our next installment in the series

Many of us have a love story with this particular fruit and consume it by itself, in ice cream, on top of pies, in compotes, and a variety of other ways. How about adding a little whipped cream? The fruit has important health benefits as well.  Yet, as migraine sufferers, we have to be acutely aware of specific triggers that we could be exposed to, including histamines found in strawberries. In this quick post, we discuss certain ways of avoiding a strawberry-induced migraine episode.

Strawberries can cause migraines

The Ideal Strawberry

I am as excited as you are to welcome summer and all the amazing freshness that comes along with the season. For migraine sufferers, this unfortunately means more work to ensure that we safely consume foods. In terms of strawberries specifically, this starts at time of purchase. We cannot simply walk by the boxes of fresh strawberries and toss a few of them in our carts. Instead, we need to carefully inspect each individual fruit. I know – it is not fun when you are rushing to get out of the store. Even after purchase,  the sides of each strawberry may need to be trimmed, regardless of a good pick. The work never ends! Picking only the best saves us time and effort later, but what are the characteristics of a safer pick?

Generally, strawberries should:

  1. Be firm to the touch – The harder the better
  2. Exhibit a lighter red color
  3. Be free from any visible deterioration on the outside, duh right…?
  4. Not display a translucent or “yellowish” color on the inside
  5. Display a maximized white center

Like everything else, taste can be a matter of opinion. Some will find a slightly sweeter and overripe strawberry preferable, while others may opt for more tartness, instead adding their favorite sweetener. Regardless, if you suffer from migraines, the former will likely be problematic. We need the ability to distinguish between the two.

Strawberries – Decent looking candidates

Better looking strawberries
Fresh Strawberry

The good thing about the pictured strawberry above is that it leaves us with ample area to work with. The size and color are both decent. Yet, as can be seen, the strawberry has some developing issues and needs to be consumed in short order.

Good Looking Strawberry

While the color is starting to change to a darker hue in the strawberry shown above, it appears perfectly fine to eat. Just to be safe, it is best to trim the sides.


Close Up of Deeper Red Strawberries
Red Strawberry

The color on the outside for this one is perhaps slightly on the redder side and the strawberry exhibits some minor deterioration, but the shape and consistency seem fine.

Fresh Strawberries
Fresh Cut Strawberry

As also seen above, the inside of this strawberry is not showing significant deterioration. However, the circled areas are starting to change color and consistency. The center-white area looks good as well.

It is possible to salvage a good portion of the strawberry as illustrated below.

Pieces of Strawberries
Fresh Trimmed Strawberry

Less Than Ideal Strawberries

A box of strawberries can go bad quickly. Even the ripest and most well preserved fruits will not last long, especially in room temperature. Refrigeration is not always going to help. As already mentioned, picking the freshest of strawberries is paramount. Taking a look at the box below, we see clear signs of deterioration. When one or more strawberries start to spoil, the entire batch can go bad very quickly.


Not So Fresh Strawberries
Box of Strawberries

By taking a closer look at the available choices in the box we can see which ones need to be discarded

Not a very good-looking candidate

Overripe Strawberry

As can be seen, the strawberry above is showing a fair amount of deterioration. The outside has gone from dark red to pink in many areas. In addition, some spoilage is already visible. It has lost some of its natural form. Even without looking at the inside of this particular one, we should probably discard but let’s quickly take a look.

Halves of Overripe Strawberries
Overripe Strawberry Cut in Half

Cutting through the strawberry, there are clear signs of over-ripeness and worse yet, spoilage. The outer edges are almost entirely translucent across the fruit. In one of the pieces, we can see the orange color clearly visible. The white center has diminished demonstrably in size. The safe bet is to discard and move on.

…more bad ones

Not So Good Looking Strawberry

Deteriorating Strawberry



Take your time choosing a box of strawberries and try not to purchase them when they are not in season. It is better to choose an underripe strawberry, as opposed to one that is overripe. You can always add your sweetener of choice if the extra sweetness in warranted. If you are worried about wasting money, do not purchase as much. It is better to go back the next day and purchase fresh strawberries.


  • ALWAYS cut up strawberries before placing in the refrigerator
  • NEVER eat past 48 hours, regardless of freshness
  • ALWAYS cut sides and top
  • NEVER add to other dishes without cutting
  • NEVER eat away from your home
  • ALWAYS wash and feel each individual strawberry
  • When in doubt ALWAYS discard

** Use the Tyramine Calculator to estimate the tyramine in your meals. **


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  • I can’t seem to eat any strawberries without a migraine in the next day or two. If it takes 2 days, I have auras the day before. Then the migraine lasts the entire day. I’ve had migraines since I was 3. Stopped having 3-5 monthly around 38 when I stopped eating strawberries. No jam (my fave way to consume), no fresh (they make my tongue peel, which is why I stopped), no compote, and now I won’t even touch artificial flavoring just in case I get too comfortable and expose myself. I eat bananas all the time, daily when I can afford it, and love them ripe (yellow, light spotting). No migraines. So, could it be something else in the strawberry causing the migraine? I’ve been trying to figure this out for 3 years and this is the first article I’ve seen mentioning them related to migraines. Nothing else gives me migraines other than really high blood pressure. No dehydration, low blood sugar or caffeine (intake or withdrawal). Just strawberries. Still trying to figure out what it is. And the tongue peeling thing started in my late 20’s. Can’t eat more than 2 fresh ones in a sitting without my tongue reacting badly. Help?

    • Thank you for the question. The short answer is yes, it could be. Without following a specific diet and eliminating and reintroducing in a clear and distinct fashion, it will be almost impossible to find out. You might actually be surprised to find that strawberries aren’t the only instigators. A suggestion would be to head over to and follow their DATA Protocol to get to the bottom.

  • I am wondering what is actually the trigger, the strawberry or the chemical changes when the strawberry spoils? My migraines have been under control for years. and strawberries are so tempting, as they have always been my favorite fruit. I haven’t had a strawberry in nearly 20 years. The same for peanuts and oranges. I am also on a medication to prevent migraines. The temptation to have a serving of strawberries is great, but I am so afraid this could start me on a cycle of migraines. My last migraine was more than 5 years ago.

    • The buildup in biogenic amines, during the aging or deterioration phase, is likely going to be the reason for our bouts of migraines when eating fruits such as strawberries. It is just not advisable to wait a day or two when having these. Instead, we need to consume them almost immediately, when fresh. Even then, it is important to properly distinguish between those that are safe and those that could pose a risk. Twenty years is a long time but, being migraine-free is well worth it. You probably know that better than anyone. Thanks for the comment.

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